Thromboembolic event rate in paroxysmal and persistent atrial fibrillation: Data from the GISSI-AF trial

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Thromboembolic event rate in paroxysmal and persistent atrial fibrillation: Data from the GISSI-AF trial

BACKGROUND Few data on the thromboembolic (TE) risk of paroxysmal and persistent atrial fibrillation (AF) are available. This study aimed to assess the incidence of TE events in paroxysmal and persistent AF. METHODS We performed a subset post hoc analysis of 771 patients with paroxysmal and 463 with persistent AF enrolled in the multicenter, prospective, randomized, double-blind, placebo-cont...

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Circulating cardiovascular biomarkers in recurrent atrial fibrillation: data from the GISSI-atrial fibrillation trial.

OBJECTIVE we evaluated the prognostic role of circulating cardiovascular biomarkers in patients with a history of recent atrial fibrillation (AF). BACKGROUND predicting long-term maintenance of sinus rhythm in patients with AF is difficult. METHODS plasma concentrations of three specific cardiac markers [high-sensitivity troponin T (hsTnT), N-terminal probrain natriuretic peptide (NT-proBNP...

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Higher risk of death and stroke in patients with persistent vs. paroxysmal atrial fibrillation: results from the ROCKET-AF Trial

AIM Anticoagulation prophylaxis for stroke is recommended for at-risk patients with either persistent or paroxysmal atrial fibrillation (AF). We compared outcomes in patients with persistent vs. paroxysmal AF receiving oral anticoagulation. METHODS AND RESULTS Patients randomized in the Rivaroxaban Once Daily Oral Direct Factor Xa Inhibition Compared With Vitamin K Antagonism for Prevention o...

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Ablation of Paroxysmal and Persistent Atrial Fibrillation

Introduction Atrial fibrillation (AF) is the most common arrhythmia in humans. Its maintenance is thought to be due to multiple wavelets reentry occurring in both atria [1]. Previous studies have demonstrated the feasibility and efficacy of cryoablation to create lesions in both atria [2] and on the posterior wall of the left atrium [3], connecting the four pulmonary veins and the mitral annulu...

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Dominant frequency increase rate predicts transition from paroxysmal to long-term persistent atrial fibrillation.

BACKGROUND Little is known about the mechanisms underlying the transition from paroxysmal to persistent atrial fibrillation (AF). In an ovine model of long-standing persistent AF we tested the hypothesis that the rate of electric and structural remodeling, assessed by dominant frequency (DF) changes, determines the time at which AF becomes persistent. METHODS AND RESULTS Self-sustained AF was...

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ژورنال

عنوان ژورنال: BMC Cardiovascular Disorders

سال: 2013

ISSN: 1471-2261

DOI: 10.1186/1471-2261-13-28